人员信息
首页研究所人员信息研究员
研究员
刘真
  • 职称：
  • 职位：研究员
  • 研究领域：
  • 电话：
  • 邮箱：zhen.liu@icpbr.ac.cn
简历

刘真博士2010年毕业于山东师范大学生命科学学院，获理学学士学位。2010年至2017年就读于中国科学院神经科学研究所，获博士学位。2017至2018年在中国科学院神经科学研究所做博士后工作。2018年担任中国科学院脑科学与智能技术卓越创新中心（原中国科学院神经科学研究所）灵长类生殖工程研究组组长。

研究方向
代表论著
1.Li, J., Zhu, Q., Cao, J., Liu, Y., Lu, Y., Sun, Y., Li, Q., Huang, Y., Shang, S.,Bian, X.,Li, C., Zhang, L.,Wang, Y., Nie, Y., Fu, J., Li, W., Mazid, M., Yu, J., Wen, J., Wang, J., Xiao,W., Sun, Y., EStban, M.,Sun, Q.*, Zhou, F.*, Liu, Z*. (2023) Cynomolgus monkey embryo model captures gastrulation and early pregnancy. Cell Stem Cell. 30（4）: 362-377.E7.

2.Chen, H. Liu, X, Li, L., Tan, Q., Li, S., Li, L., Li, C., Fu, J., Lu, Y., Wang, Y., Sun, Y., Luo, Z.*, Lu, Z., Sun, Q.*, Liu, Z*. (2023) CATI: an efficient gene integration method for rodent and primate embryos by MMEJ suppression. Genome Biology. 24: 146

3.Zhu, W., Ding, Y., Meng, J., Gu, L., Liu, W., Li, L., Chen, H., Wang, Y., Li, Z., Li, C.*, Sun, Y.*, Liu, Z*. (2023) Reading and writing of mRNA m6A modification orchestrate maternal-to-zygotic transition in mice. Genome Biology. 67(2023).

4.Li, L., Liu, Z*. (2023) Genetic Approaches for Neural Circuits Dissection in Non-human Primates. Neuroscience Bulletin : In Press.

5.Lu, Z., He, S., Jiang, J., Zhuang, L., Wang, Y., Yang, G., Jiang, X., Nie, Y., Fu, J., Zhang, X., Lu, Y., Bian, X., Chang, H., Xiong, Z., Huang, X*., Liu, Z*., Sun, Q*. (2022) Base-edited cynomolgus monkeys mimic core symptoms of STXBP1 encephalopathy. Molecular Therapy. 30: 2163-2175.

6. Liu, Z*., Li, K., Cai, Y., Liu, Q., Zhang, T., Lu, Y., Nie, Y., Wang, Y., Yan, Z., Qu, Y., Li, Y., Wang, Z., Xiong, Z.*, Sun, Q.* (2021) Accelerated passage of gene-modified monkeys by hormone-induced precocious puberty. National Science Review. 10: 1093

7. Liu, Z., Cai, Y.,Wang, Y.,Wang, Z.,Jiang, X.,Li, Y.,Nie, Y.,Zhang, X.,Li, C.,Bian, X.,Poo, M.,Chang, H.*,Sun, Q.* (2019) Cloning of a Gene-edited Macaque Monkey by Somatic Cell Nuclear Transfer. National Science Review. 6: 101-108

8.Liu, Z., Cai, Y.,Wang, Y.,Nie, Y.,Zhang, C.,Xu, Y.,Zhang, X.,Lu, Y.,Wang, Z.,Poo, M.,Sun, Q.* (2018) Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer. Cell 172: 881-887

9. Liu, Z., Li, X.,Zhang, T.,Cai, Y.,Cheng, L.,Cheng, C.,Wang, Y.,Zhang, C.,Nie, Y.,Chen, Z.,Bian, W.,Zhang, L.,Xiao, J.,Lu, B.,Zhang, Y.,Zhang, X.,Sang, X.,Wu, J.,Xu, X.,Xiong, Z.,Zhang, F.,Yu, X.,Gong, N.,Zhou, W.,Sun, Q.*，Qiu, Z.* (2017) Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2 . Nature 530: 98-102

10. Liu, Z., Nie, Y.,Zhang, C.,Cai, Y.,Wang, Y.,Lu, H.,Li, Y.,Cheng, C.,Qiu, Z.,Sun, Q.* (2015) Generation of macaques with sperm derived from juvenile monkey testicular xenografts. Cell Research. 26: 139–142