The C³ Lab investigates the neural mechanisms and biomarkers of cognitive control — the brain’s feedback loop that monitors outcomes and adapts future behavior. These processes are fundamental to flexible interaction with the world, yet are disrupted in major psychiatric and neurological disorders.

Our research emphasizes adaptive behavior in dynamic and uncertain environments, where events are probabilistic and causes of errors are often ambiguous. Imagine waiting at a bus stop: at what point do you stop waiting and seek another option? Such situations require learning statistics, making inferences, and updating internal models across multiple timescales. Similarly, if a cup tips over, was it your action or the table shaking? The adjustment depends on the inferred cause.

To study these mechanisms, we combine human EEG and behavioral measures with novel monkey experiments, including interareal laminar recordings in frontal cortex and simultaneous intracranial and EEG recordings. This integrative approach links circuit mechanisms to non-invasive biomarkers, building a translational bridge from basic neuroscience to mental health applications.