We focus on the important questions of embryology, reproduction and stem cells in primate species. It includes somatic cell nuclear transfer and cell reprogramming, embryonic stem cell pluripotency, germ cell differentiation and spermatogonia stem cell culture. These studies will provide new potential transgenic technologies for non-human primates and new solutions for human reproductive barriers.

we spare great efforts in developing genetic tools for monkey brain study by taking advantage of our experience in primate gene manipulation. We aim to achieve precise access of different cell type in monkey brain by Cre knock-in model generation and specific enhancer screening. We are also developing genetic tools used for neuron activity manipulation via optogenetics and neuron activity monitoring via calcium imaging. These genetic tools development will benefit monkey brain atlas and brain structure study, brain function and cognitive study, and also optical brain-computer interface study.