Natural stimuli modulate the activity of visual cortex on a variety of temporal scales, yet it is still unclear whether visual cortical neurons employ more than one response time scale to encode such stimuli. We investigated this issue by analyzing the activity of neurons recorded in primary visual cortex (V1) of anesthetized macaques during binocular presentation of naturalistic color movies, and we used information theory to quantify the amount of information carried by neural codes operating at different temporal scales. We divided the recording time into stimulus windows of 4080 ms, and we computed the information carried by the neural response in each window about which stimulus window was being shown. First we measured the information carried by the spike count, simply quantified by the total number of spikes in the stimulus window. Then we measured the information carried by the temporal pattern of spikes, the latter being computed by subdividing each stimulus window into smaller time bins of size 攖 and converting the spike train into a sequence of 0s and 1s denoting the absence/presence of spikes inside each bin [1]. When considering temporal patterns of spikes with a temporal resolution 攖 of 8 or 16 ms, the information about which part of the movie was being shown conveyed by temporal spike patterns was up to 15% more than that conveyed by the spike count. This information gain did not increase further when considering resolutions finer than 8 ms, indicating that spike patterns carry information with a resolution of 816 ms or coarser. A previous study [2] showed that V1 neurons encode information also with respect to the phase of low frequency (1–4 Hz range) Local Field Potential (LFP) fluctuations. We investigated whether spike patterns carried informa