Postdocs--International Center For Primate Brain Research

Postdocs

XU Yangfeng

Department：
Position：Postdoctoral Researcher
Research Field：Brain stimulation, Brain imaging, Veterinary medicine, Translational Psychiatry
Phone：
E-mail：yangfeng.xu@icpbr.ac.cn

Biography

Yangfeng obtained his bachelor’s degree in veterinary medicine at Southwest University (Supervisor: Prof. Dr. Juan Liu). Then he moved to Guangxi University and pursued the master degree in veterinary pharmacology and toxicology (Supervisor: Prof. Dr. Jiakang He). He received his PhD in health sciences from Ghent University (Supervisor: Prof. Dr. Chris Baeken, Dr. Kathelijne Peremans, Prof. Dr. Jimmy Saunders). During his PhD, he combined neurostimulation treatment (accelerated repetitive Transcranial Magnetic Stimulation (rTMS)) with multimodal brain imaging techniques (MRI/SPECT/PET) in a canine model to evaluate and treat anxiety dogs, bridging the gap between human and veterinary research. Now he joins the laboratory of dynamic embodied brain at ICPBR, focusing on the functional organization of the insular cortex.

Research Interests

Interoception, Brain stimulation, Brain imaging, Veterinary medicine, Translational Psychiatry

Selected Publications

1.Yangfeng Xu, Kathelijne Peremans, Sofie Salden, Kurt Audenaert, Andre Dobbeleir, Ann Van Eeckhaut, Dimitri De Bundel, Jimmy H. Saunders, Chris Baeken. 2023. Accelerated high frequency rTMS induces time-dependent dopaminergic alterations: a DaTSCAN brain imaging study in healthy beagle dogs. Frontiers in Veterinary Science, 10.

2.Qinyuan Chen*, Yangfeng Xu*, Emma Christiaen, Guo-Rong Wu, Sara De Witte, Christian Vanhove, Jimmy Saunders, Kathelijne Peremans, Chris Baeken. 2023. Structural connectome alterations in anxious dogs: a DTI-based study. Scientific Reports, 13(1): 9946.

3.Yangfeng Xu*, Emma Christiaen*, Sara De Witte, Qinyuan Chen, Kathelijne Peremans, Jimmy Saunders, Christian Vanhove, Chris Baeken. 2023. Network analysis reveals abnormal functional brain circuitry in anxious dogs. PLOS ONE, PONE-D-22-02320.

4.Yangfeng Xu, Kathelijne Peremans, Jan Courtyn, Kurt Audenaert, Andre Dobbeleir, Yves D'Asseler, Eric Achten, Jimmy Saunders, Chris Baeken. 2022. The Impact of Accelerated HF-rTMS on Canine Brain Metabolism: An [(18)F]-FDG PET Study in Healthy Beagles. Frontiers in Veterinary Science 9:800158.

5.Yangfeng Xu, Mitchel Kappen, Kathelijne Peremans, Dimitri De Bundel, Ann Van Eeckhaut, Nick Van Laeken, Filip De Vos, Andre Dobbeleir, Jimmy Saunders, Chris Baeken. 2022. Accelerated HF-rTMS Modifies SERT Availability in the Subgenual Anterior Cingulate Cortex: A Canine [11C] DASB Study on the Serotonergic System. Journal of Clinical Medicine 11 (6):1531.

6.Chris Baeken, Yangfeng Xu, Guo-Rong Wu, Robrecht Dockx, Kathelijne Peremans, Rudi De Raedt. 2021. Hostility in medication-resistant major depression and comorbid generalized anxiety disorder is related to increased hippocampal– amygdala 5-HT2A receptor density. European Archives of Psychiatry and Clinical Neuroscience 271 (7):1369-1378.

7.Yangfeng Xu, Guoqing Yan, Xuemei Wen, Liqin Wu, Ruihan Deng, Qiuling Liang, Linjie Zhang, Hangping Chen, Xin Feng, Jiakang He. 2022. Preparation, evaluation, and pharmacokinetics in beagle dogs of a taste-masked flunixin meglumine orally disintegrating tablet prepared using hot-melt extrusion technology and D-optimal mixture design. European Journal of Pharmaceutical Sciences 168:106019.

8.Yangfeng Xu, Xuemei Wen, Xin Feng, Zhengmin Liang, Xingyou Ye, Haiying Nie, Xiaoguang Liao, Jinhui Li, Yun Zeng, Shusheng Tang, Jiakang He. 2018. Preparation, characterization, and pharmacokinetics in swine of a florfenicol enteric formulation prepared using hot‐melt extrusion technology. Journal of veterinary pharmacology and therapeutics 41 (4):572-580.